Quantifying Hepatic Steatosis by MRI

Hepatic steatosis was evaluated by magnetic resonance imaging (MRI) using a 3.0 T Ingenia MRI system (Philips Healthcare) with a dStream torso coil and evaluated at baseline and following 6 weeks’ diet intervention. Total hepatic fat fractions were measured by single-voxel MR spectroscopy (Point RESolved Spectroscopy [PRESS]) [31 (link), 32 (link)]. These data have been published previously [26-29 (link)].

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Kjeldsen S.A., Thomsen M.N., Skytte M.J., Samkani A., Richter M.M., Frystyk J., Magkos F., Hansen E., Thomsen H.S., Holst J.J., Madsbad S., Haugaard S.B., Krarup T, & Wewer Albrechtsen N.J. (2023). Markers of Glucagon Resistance Improve With Reductions in Hepatic Steatosis and Body Weight in Type 2 Diabetes. Journal of the Endocrine Society, 7(11), bvad122.

Publication 2023

Ingenia MRI system dStream torso coil

Corresponding Organization : University of Copenhagen

Other organizations : Odense University Hospital, Herlev Hospital, Hvidovre Hospital

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Variable analysis

independent variables

Diet intervention

dependent variables

Total hepatic fat fractions

control variables

Baseline measurement of total hepatic fat fractions
Use of a 3.0 T Ingenia MRI system (Philips Healthcare) with a dStream torso coil
Use of single-voxel MR spectroscopy (Point RESolved Spectroscopy [PRESS])

controls

Baseline measurement of total hepatic fat fractions

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