This study retrospectively analyzed the data for a large cohort of patients with IC/BPS. The study included patients who attended our hospital between October, 1997 and March, 2019 with clinical symptoms of urinary frequency, urgency, and nocturia, with or without bladder pain. Patients had been treated with lifestyle modification and medication for the bladder symptoms such as antimuscarinics, beta-3 adrenoceptor agonists, and non-steroid anti-inflammatory agents (NSAID) but the bladder symptoms remained. Patients with chronic urinary retention, acute or chronic urinary tract infection, urodynamic stress incontinence, pelvic organ prolapse, possible neurogenic voiding dysfunction, previous genital tract or lower urinary tract surgery, previous irradiation, or a previous history of genitourinary tract malignancy were excluded from the analysis. All the patients underwent a videourodynamic study (VUDS) and cystoscopic HD examination. Based on the VUDS results, patients with intrinsic sphincter deficiency, neurogenic bladder, or overt bladder outlet obstruction were excluded from the analysis.
Finally, 486 patients were diagnosed to have IC/BPS and included in this study (65 men, 421 women). Data for their baseline clinical symptoms, disease duration, medical co-morbidity, urodynamic findings, and cystoscopic characteristics (MBC, glomerulations, and Hunner’s lesion) were extracted from the medical records. This included scores for the ICSI, Interstitial Cystitis Problem Index (ICPI), and O’Leary–Sant Symptom index (OSS)25 (link).
The study was approved by the Research Ethics Committee of the Hualien Tzu Chi Hospital (IRB: 105-25-B). Because of the retrospective nature of the study, the requirement for informed consent was waived. All methods used in this study were carried out in accordance with relevant guidelines and regulations.
Finally, 486 patients were diagnosed to have IC/BPS and included in this study (65 men, 421 women). Data for their baseline clinical symptoms, disease duration, medical co-morbidity, urodynamic findings, and cystoscopic characteristics (MBC, glomerulations, and Hunner’s lesion) were extracted from the medical records. This included scores for the ICSI, Interstitial Cystitis Problem Index (ICPI), and O’Leary–Sant Symptom index (OSS)25 (link).
The study was approved by the Research Ethics Committee of the Hualien Tzu Chi Hospital (IRB: 105-25-B). Because of the retrospective nature of the study, the requirement for informed consent was waived. All methods used in this study were carried out in accordance with relevant guidelines and regulations.
Free full text: Click here
