Participants featured in the current study were enrolled into SUCCEED starting in November 2003 and ending in September 2007. We recruited women referred to colposcopy at the University of Oklahoma Dysplasia Clinic based at the University of Oklahoma Health Sciences Center (OUHSC), with a recent abnormal Pap smear diagnosis or a biopsy diagnosis of CIN. Details of study design and inclusion criteria have been described elsewhere (11 (link)). Briefly, exclusion criteria included women who were less than 18 years-of-age, pregnant at the time of their visit, previously treated with chemotherapy or radiation for any cancer, or women scheduled for vaginal colposcopy. Written informed consent was obtained from all women enrolled into the study and Institutional Review Board approval was provided by OUHSC and the U.S. National Cancer Institute.
At the time of the analysis, 1899 women had been enrolled; of these, we excluded 16 from the present analyses due to missing HPV results and further excluded 213 women due to unsatisfactory cytology, constituting a study population of 1670 women with a median age of 25 years (18–81 years). Of these, the following groups were excluded from the analyses of type attribution in cervical disease, because they could not be assigned to a disease category: 41 women with negative cytology, histology, and HPV result, 73 women without histology result and nine women without cytology result in the
At the time of the analysis, 1899 women had been enrolled; of these, we excluded 16 from the present analyses due to missing HPV results and further excluded 213 women due to unsatisfactory cytology, constituting a study population of 1670 women with a median age of 25 years (18–81 years). Of these, the following groups were excluded from the analyses of type attribution in cervical disease, because they could not be assigned to a disease category: 41 women with negative cytology, histology, and HPV result, 73 women without histology result and nine women without cytology result in the
