Simultaneous Integrated Boost in VMAT Radiotherapy

All HNC plans were created with a simultaneous integrated boost (SIB) technique using 6MV photons and 2 full RapidArc™ (Varian Medical Systems, Palo Alto, USA) arcs. In 35 fractions, plans aimed to deliver 95 % of the prescribed dose of 54.25Gy/70.0Gy to 98 %/99 % of the elective/boost PTV (PTV_E/PTV_B), while limiting the volume of each PTV receiving >107 % of the prescribed dose. A 5mm transition zone (PTV_T) was created between PTV_E and PTV_B to facilitate dose fall-off between them. The optimization goals and included OARs have been outlined in detail previously [7 (link), 19 (link)–21 (link)].

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Tol J.P., Dahele M., Delaney A.R., Slotman B.J, & Verbakel W.F. (2015). Can knowledge-based DVH predictions be used for automated, individualized quality assurance of radiotherapy treatment plans?. Radiation Oncology (London, England), 10, 234.

Publication 2015

RapidArc

Arcs Plans

Corresponding Organization : Amsterdam UMC Location VUmc

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Variable analysis

independent variables

Simultaneous integrated boost (SIB) technique
6MV photons
2 full RapidArc™ (Varian Medical Systems, Palo Alto, USA) arcs

dependent variables

Dose delivered to 98 %/99 % of the elective/boost PTV (PTV_E/PTV_B)
Volume of each PTV receiving >107 % of the prescribed dose

control variables

35 fractions
Prescribed dose of 54.25Gy/70.0Gy
5mm transition zone (PTV_T) between PTV_E and PTV_B

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