18F-Fluciclatide was manufactured at the Clinical Research Imaging Centre on an automated module (FASTlab synthesiser; GE Healthcare) by coupling an amino-oxy-functionalised peptide precursor (AH111695) with 4–18F-fluorobenzaldehyde at pH 3.5 to form 18F-fluciclatide.17 (link) A full description of this synthesis has been published previously.16 (link)
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