Transgenic Mouse Lines for Auditory Research

Plp-CreER^T mice (stock #5975, Doerflinger et al., 2003 (link)), Rosa26^tdTomato mice, also referred to as Ai14 (stock #7914, Madisen et al., 2010 (link)), and Atoh1^GFP/+ mice (stock #13593, Rose et al., 2009 (link)) were obtained from The Jackson Laboratory. Pou4f3^DTR mice (Golub et al., 2012 (link); Tong et al., 2015 (link)) were provided by Dr. Ed Rubel (University of Washington, Seattle, WA, USA). Prox1^CreERT2 mice (Srinivasan et al., 2007 (link)) were provided by Dr. Guillermo Oliver (St. Jude Children’s Research Hospital, Memphis, TN, USA). Both of these strains are now available at The Jackson Laboratory. Transnetyx, Inc., performed all genotyping. Mice of both genders were used, and all animal work was performed in accordance with approved animal protocols from the Institutional Animal Care and Use Committee at Southern Illinois University School of Medicine.