Production of NADH and NADPH was measured using, respectively, the NAD/NADH kit (Abcam, Cambridge, UK) and the NADP/NADPH kit (Abcam) according to the manufacturer's instruction. Lactate and LDH activity were measured using the Roche diagnostic kit on a Cobas 8000 (Roche Diagnostics, Mannheim, DE, USA) as described previously.39 (link)
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