The bioactive molecule profile of cinnamon extract before and after digestion and the methodology utilised for the analyses were reported in a previous paper [9 (link)]. Briefly, a Thermo Vanquish UHPLC system coupled with a Thermo Orbitrap Exploris 120 mass spectrometer and a Vanquish Diode Array Detector (Thermo Scientific, Rodano, Italy) was used to identify the target bioactive molecules. The chromatographic separation was carried out on a Luna Omega Polar C18 (150 mm × 2.1 mm, 3 µm) (Phenomenex, Castelmaggiore, Italy). Phenolic compounds were identified based on the corresponding spectral characteristics (UV and MS/MS spectra), accurate molecular mass, characteristic MS fragmentation pattern, and library comparison in a semi-automatic way through Compound Discoverer Software (2.1, Thermo Scientific, Rodano, Italy). A semi-quantification was carried out to reveal the changes in the compound composition of the cinnamon extract before and after digestion. All compounds were quantified in duplicate at 280 nm by external calibration lines, dividing them into two major groups according to their structural similarity: trans-cinnamic acid or catechin. The data are reported in Pagliari et al., 2023 [9 (link)].
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