Example 5
According to the teachings herein, one or more peptides comprising a lipoprotein targeting domain and a protease inhibitor domain, optionally further including therebetween a linker, can be placed in a suitable container, such as a tissue microcapsule implant, and placed within a subject to allow continuous, slow release of one or more of the disclosed peptides. Such peptides can either be provided in the free state or after complexation with lipid (e.g., in the form of a loaded or enriched nHDL or rHDL).
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