We excluded multiple inclusions and analyses of the same AE as well as irrelevant studies. An irrelevant study was defined as a non-case report, such as a review, commentary, or clinical trial.
AEs reporting infection, internal organ or tissue injury, and other severe consequences are categorized as “complications,” defined as an added difficulty; a complex state; a disease or accident superimposed upon another without being specifically related. Peripheral or secondary effects such as syncope, nausea, or immune reactions are classified as “adverse reactions” [5 (link)].