Our in vivo 1H-MRS data come from a single, 12 cubic centimeters (cc) spectroscopic voxel in the anterior cingulate region of the human brain localized by point-resolved spectroscopy (PRESS), acquired with a TIM Trio 3-Tesla whole-body scanner (Siemens Medical Solutions, Erlangen, Germany; Syngo MR B15), using a 12-channel head coil receiver in conjunction with body coil excitation (TR/TE = 2 sec/40 msec, dwell time = 0.625 msec). The voxel is prescribed using a T1 scout image, and two sets of data, a water-suppressed data averaged from 192 fid signals and an unsuppressed water data averaged from 16 fid signals were obtained from the voxel. The acquired time series 1H-MRS data are stored in our data archive, for postacquisition analysis (Bockholt et al. 2010 (link)).
Data used in our analysis comes from 206 subjects (129 male, 76 female; ages 18–54), all patients, enrolled in three of our substance-abuse studies. All subjects provided informed consent to participate in these studies conducted at The Mind Research Network, Albuquerque, NM in accordance with protocols approved by the human research review committee of the University of New Mexico.
Data used in our analysis comes from 206 subjects (129 male, 76 female; ages 18–54), all patients, enrolled in three of our substance-abuse studies. All subjects provided informed consent to participate in these studies conducted at The Mind Research Network, Albuquerque, NM in accordance with protocols approved by the human research review committee of the University of New Mexico.
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