As previously described (18 (link), 19 (link)), dorsoplantar widths of the hind feet were measured using a Mitutoyo Corporation dial thickness gauge every 2-3 days from D11 until sacrifice. Right and left footpad widths from each rat were averaged, and then mean footpad widths from rats within each group were averaged and expressed as a mean ± standard error of the mean (SEM). The hind limbs were photographed under anesthesia.
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