Western blotting and immunohistochemistry (IHC) methods were performed as described previously [22 (link)]. The IHC quantitation analysis was calculated by ImageJ software and statistically analyzed in three random fields. The antibodies used were as follows: anti-ISG20 antibody (Proteintech, Wuhan, China), anti-SEH1L antibody (Sigma, St. Louis, MO, USA), and anti-ERK1/2 antibody (Cell Signaling Technology, Danvers, MA, USA).
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