Phospholipid Modulation of Antibiotic Susceptibility

Various phospholipids, such as phosphatidylglycerol (PG, Aladdin,
China), Phosphatidylethanolamine (Y0001953, Sigma-Aldrich, USA), or
cardiolipin (CL, Sigma-Aldrich, C0563, USA), were dissolved in methanol.
The impact of phospholipids (ranging from 1 to 128 μg/mL) on
the MIC values of candesartan cilexetil in CAMHB medium was assessed
using the checkerboard method as described.^{23 (link)}

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Chen C., Li D., Shang Y., Lin Z., Wen Z., Li P., Yu Z., Chen Z, & Liu X. (2024). Antibacterial Activity and Mechanism of Candesartan Cilexetil against Enterococcus faecalis. ACS Omega, 9(19), 21510-21519.

Publication 2024

Corresponding Organization : Union Hospital

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Variable analysis

independent variables

Concentration of phospholipids (ranging from 1 to 128 μg/mL)

dependent variables

MIC values of candesartan cilexetil in CAMHB medium

control variables

CAMHB medium

controls

No positive or negative controls were explicitly mentioned.

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