Urinary Phytoestrogen Metabolite Profiles

The levels of isoflavone metabolites, daidzein (ng/mL), equol (ng/mL), genistein (ng/mL), and O-desmethylangolensin (ODMA, ng/mL) as well as lignan metabolites, enterodiol (ng/mL) and enterolactone (ng/mL) in the urine were measured by high-performance liquid chromatography-atmospheric pressure photoionization-tandem mass spectrometry. The association between urinary phytoestrogen levels and isoflavone intake in the years 2007–2010 was analyzed using the Pearson correlation method.

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Zhou F., Gu K, & Zhou Y. (2023). Flavonoid intake is associated with lower all-cause and disease-specific mortality: The National Health and Nutrition Examination Survey 2007–2010 and 2017–2018. Frontiers in Nutrition, 10, 1046998.

Publication 2023

Atmospheric pressure Daidzein Enterodiol Enterolactone Equol Genistein High performance liquid chromatography Isoflavone Lignan O desmethylangolensin Phytoestrogen Tandem mass spectrometry Urine

Corresponding Organization :

Other organizations : Jiangnan University, Wuxi Fourth People's Hospital

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Variable analysis

independent variables

Isoflavone intake in the years 2007-2010

dependent variables

Levels of isoflavone metabolites, daidzein (ng/mL), equol (ng/mL), genistein (ng/mL), and O-desmethylangolensin (ODMA, ng/mL)
Levels of lignan metabolites, enterodiol (ng/mL) and enterolactone (ng/mL)

control variables

Urinary phytoestrogen levels

controls

No positive or negative controls were explicitly mentioned in the provided information.

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