MCR syndrome was diagnosed based on established criteria[1 (link), 2 (link), 5 (link)] as the presence of subjective cognitive complaints and slow gait in older individuals without dementia or mobility disability. MCR builds on definitions of MCI; substituting impairment on cognitive tests criterion in MCI with the criterion of slow gait. Cognitive complaints were based on responses by participants to standardized questions about memory as a part of the Health Self-Assessment Questionnaire and from the Geriatric Depression Scale[5 (link)]. Gait speed was measured using an 8.5 meter long computerized walkway with embedded pressure sensors (GAITRite; CIR Systems, PA). The GAITRite system is widely used in clinical and research settings, and excellent reliability has been reported in our and other centers[13 (link), 14 (link)]. Participants walked on the walkway at their normal pace in a quiet well-lit room wearing comfortable footwear and without any attached monitors. Slow gait was defined as walking speed one standard deviation (SD) or more below age and sex specific means as described in previous MCR studies in the LonGenity cohort[2 (link), 5 (link)]. Dementia was diagnosed at consensus case conference after review of all available clinical, neuropsychological and medical information[15 (link)].