Troponin Measurement in Myocardial Injury

Blood samples were drawn from a peripheral vein and hsTnT was measured using the new quantitative electrochemiluminescence immunoassay (Cobas 411, Roche Diagnostics, Mannheim, Germany), as described previously [17 (link)]. A concentration of 14 ng/L has been identified as the 99th percentile of a healthy reference population with a coefficient of variability of <10% [18 (link)]. Chronic myocardial injury was defined as increased but stable troponin levels in terms of a rise/fall ≤20% in serial measurements, and acute myocardial injury was defined as the rise or fall of troponin >20% in serial measurements [19 (link),20 (link)].