Genetically Modified Mouse Strains

Non-transgenic C57Bl/6 mice were obtained from Charles River (Manston, Kent, UK), Envigo (Huntingdon, UK and Indianapolis IN) or Janvier Labs (Le Genest-Saint-Isle, France). Pomc^eGFP, Cck^ires-Cre, Crh^ires-Cre (Taniguchi et al., 2011 (link)), Slc17a6^ires-Cre and Rosa26-loxSTOPlox-eYFP were all purchased from Jackson Laboratories (stock numbers 009593, 012706, 012704, 016963 and 006148, respectively; Bar Harbor, ME). We have described the generation of the PPG (Gcg^Cre) and PrRP (Prlh^ires-Cre) mice (Parker et al., 2012 (link); Dodd et al., 2014 (link)). Calca^ires-Cre mice (Carter et al., 2013 (link)) were a kind gift from Prof Richard Palmiter (Howard Hughes Medical Institute, University of Washington).