Gene Expression Profiling of Myeloproliferative Neoplasms

Key word “myeloproliferative neoplasms” was used to search gene expression profiles of MPNs in the Gene Expression Omnibus (GEO, http://www.ncbi.nlm.nih.gov/geo/) data portal. The following criteria were used to filter the obtained database: 1. The gene expression profiling must cover all types of chronic and progressed MPNs (PV, ET, PMF) and controls. 2. The cell used for sequencing should be CD34⁺ MNCs (mononuclear cell) from peripheral blood (PB) or bone marrow (BM). 3. The processed data or raw data from datasets must be provided thus could be available to reanalyze. 4. The GEO dataset numbered GSE136335, GSE145802 were selected. Further, anoikis-related genes (ARGs) were downloaded from the GeneCard database (https://www.genecards.org/).