IDF-11774 (S8771, purity > 99%; Selleckchem, Houston, TX) was prepared as stock solution in dimethyl sulfoxide (DMSO) at 10 mM and stored at –20°C. In brief, 10 μM IDF-11774 was supplemented in cell culture, while 20 mg/kg/day IDF-11774 was administered orally to mice, according to previous methods (21 (link)).
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