Estimating SARS-CoV-2 Vaccine Effectiveness

The differences in the characteristics between the infected and uninfected groups were estimated using the chi-square test for categorical variables, and the 2-sample t-test for continuous variables. A p<0.05 was considered to indicate statistical significance. R ver. 4.1.0 (The R Foundation, Vienna, Austria; https://www.r-project.org/) was used to perform the statistical analysis. Regarding vaccination history, the RR of vaccinated and unvaccinated groups was calculated and compared to determine the risk of SARS-CoV-2 infection, and VE was evaluated based on the calculated RR reduction using the following formula [19 (link)]:

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Kim C., Kang G., Kang S.G, & Lee H. (2022). COVID-19 outbreak response at a nursing hospital in South Korea in the post-vaccination era, including an estimation of the effectiveness of the first shot of the Oxford-AstraZeneca COVID-19 vaccine (ChAdOx1-S). Osong Public Health and Research Perspectives, 13(2), 114-122.

Publication 2022

R ver. 4.1.0

Sars cov 2 infection Vaccination

Corresponding Organization :

Other organizations : Government of the Republic of Korea

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Variable analysis

independent variables

Vaccination history

dependent variables

Risk of SARS-CoV-2 infection
Vaccine Effectiveness (VE)

control variables

Kept constant to ensure valid results

Annotations

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