The strains and plasmids are listed in Table 1 . Staphylococcus sp. Z01 and Micrococcus sp. Z02 were isolated from marine biofilm grown on Petri dishes (Corning Inc., New York, United States) in a subtidal zone as described in Wang et al. (2020) (link). The 16S rRNA genes amplicon was performed using 8F/1492R primers, followed by Sanger sequencing in BGI (Beijing, China). BLAST searches on the NCBI 16S ribosomal RNA sequences database and EzBioCloud database was performed on the obtained sequences to identify the taxonomy of the isolates. The 16S rRNA gene sequence of Micrococcus sp. has 94.7% of similarity to Micrococcus yunnanensis, and that of Staphylococcus sp. has 96.2% of similarity to Staphylococcus warneri.
Albofungins were isolated and purified as previously described (She et al., 2021 (link)). The purity of tested compounds was confirmed by high-performance liquid chromatography (95% purity, HPLC, Waters 2695, Milford, MA, United States), and their structures were determined by the Bruker NMR spectrometers (Bruker, Billerica, MA, United States) and X-ray crystallography as previously described (Ye et al., 2020 (link); She et al., 2021 (link)).
Albofungins were isolated and purified as previously described (She et al., 2021 (link)). The purity of tested compounds was confirmed by high-performance liquid chromatography (95% purity, HPLC, Waters 2695, Milford, MA, United States), and their structures were determined by the Bruker NMR spectrometers (Bruker, Billerica, MA, United States) and X-ray crystallography as previously described (Ye et al., 2020 (link); She et al., 2021 (link)).
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