ABCD Neuroimaging Protocol for LPFC

The lateral prefrontal cortex (LPFC) variables were derived from the ABCD structural magnetic resonance imaging (sMRI) module.²⁶ The ABCD study consortium conducted and preprocessed all neuroimaging data. Morphologic features (eg, volume and thickness) of the LPFC and its subregions (eg, lateral orbitofrontal cortex [LOFC], middle frontal gyrus [MFG], and inferior frontal gyrus [IFG]) were estimated using Freesurfer version 5.3.0 (Freesurfer).^{27 (link)} Brain imaging was performed at wave 1 and wave 3 data collection. The methods of the brain imaging protocol are published elsewhere.^{28 (link)}