Substituted aryl halides (0.25 mmol, 1 eq.) and terminal alkynes (0.3 mmol, 1.2 eq.) were added to a mixture of water : ethanol (4 mL) and placed in 10 mL Monowave 50 vial. After adding potassium carbonate (0.75 mmol, 3 eq.) and catalyst 3 (7.50 mg, 5.0 μmol, 2 mol%), the reaction mixture was heated at 120 °C for 20 minutes (or the time indicated in Table 4) in Monowave 50 heating reactor in a sealed vial. Upon the completion of the reaction, the mixture was extracted with dichloromethane (2 × 5 mL). The organic layers were combined, dried over sodium sulfate, and filtered. The solvent was removed in vacuo and the final products was purified by flash chromatography on silica gel using hexane: ethyl acetate as the eluent.