Florbetapir PET Brain Imaging Protocol

Approximately 50 minutes after florbetapir (370 MBq) administration, the GE Discovery ST-16 PET/CT Scanner acquired two continuous 5-minute PET brain frames. We summed and attenuation corrected the frames. We then calculated standardized uptake value ratio to the whole cerebellum (SUVR) using a custom processing pipeline in SPM12 (http://www.fil.ion.ucl.ac.uk/spm), described previously.^{30 (link)}

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Kaufman C.S., Morris J.K., Vidoni E.D., Burns J.M, & Billinger S.A. (2021). Apolipoprotein E4 moderates the association between vascular risk factors & brain pathology. Alzheimer disease and associated disorders, 35(3), 223-229.

Publication 2021

Discovery ST-16

Brain Cerebellum Ct scanner Florbetapir Frames

Corresponding Organization : University of Kansas Medical Center

Other organizations : University of Kansas

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Variable analysis

independent variables

Florbetapir (370 MBq) administration

dependent variables

Standardized uptake value ratio to the whole cerebellum (SUVR)

control variables

GE Discovery ST-16 PET/CT Scanner
Acquisition of two continuous 5-minute PET brain frames
Summing and attenuation correction of the frames
Custom processing pipeline in SPM12

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