Inhibition of Geranylgeranylation in Cells

Brefeldin A and GGTI-2133 were obtained from Sigma-Aldrich (St Louis, MO, USA). Professor David Wiemer at the University of Iowa kindly provided the GGDPSi VSW1198 [8 (link)] and RAM2061 [10 (link)], as well as the GGTase II inhibitor NHB2005 [31 (link)].

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Haney S.L., Varney M.L., Chhonker Y.S., Shin S., Mehla K., Crawford A.J., Smith H.J., Smith L.M., Murry D.J., Hollingsworth M.A, & Holstein S.A. (2019). Inhibition of geranylgeranyl diphosphate synthase is a novel therapeutic strategy for pancreatic ductal adenocarcinoma. Oncogene, 38(26), 5308-5320.

Publication 2019

Brefeldin A GGTI-2133

Brefeldin a Ggtase ii Ggti 2133 University professor Vsw1198

Corresponding Organization :

Other organizations : University of Nebraska Medical Center

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Variable analysis

independent variables

Brefeldin A
GGTI-2133
GGDPSi VSW1198
RAM2061
NHB2005

dependent variables

Not explicitly mentioned

control variables

Not explicitly mentioned

positive controls

Not specified

negative controls

Not specified

Annotations

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