Measurement of Transdiaphragmatic Pressure

The Pdi was calculated by subtraction of the esophageal pressure (Pes) from the gastric pressure (Pga), ie, (Pdi = Pga − Pes). The Pes and Pga were measured by one double-lumen catheter separately opening into two latex balloons (Figure 3) respectively positioned 10 cm above the cardia and in the stomach. Furthermore, the two latex balloons were respectively filled with 0.5 mL and 1–2 mL of air.11 (link) The mouth pressure (Pm) was measured by detecting the pressure in the mouthpiece.12 (link) The mouthpiece and the two lumens of the catheter were respectively coupled to three pressure transducers (MLT844; ADInstruments, Bella Vista, NSW, Australia) that were connected to the biological signal acquisition and analysis system (Powerlab 16/35; ADInstruments) via a four-channel bridge amplifier (FE224; ADInstruments). The flow rate was obtained by using a pressure differential pneumotachograph (MLT300L; ADInstruments).

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Wu W., Zhang X., Lin L., Ou Y., Li X., Guan L., Guo B., Zhou L, & Chen R. (2017). Transdiaphragmatic pressure and neural respiratory drive measured during inspiratory muscle training in stable patients with chronic obstructive pulmonary disease. International Journal of Chronic Obstructive Pulmonary Disease, 12, 773-781.

Publication 2017

MLT844 Powerlab 16/35 FE224 MLT300L

Biological Cardia Catheter Latex Mouth Pressure Pressure transducers Stomach

Corresponding Organization :

Other organizations : State Key Laboratory of Respiratory Disease, Guangzhou Medical University, First Affiliated Hospital of Guangzhou Medical University, Affiliated Hospital of Guizhou Medical University, Guiyang Medical University

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Variable analysis

independent variables

None explicitly mentioned

dependent variables

Diaphragmatic pressure (Pdi)
Esophageal pressure (Pes)
Gastric pressure (Pga)
Mouth pressure (Pm)
Flow rate

control variables

Positioning of the two latex balloons: 10 cm above the cardia and in the stomach
Amount of air filled in the two latex balloons: 0.5 mL and 1-2 mL, respectively

controls

No positive or negative controls were explicitly mentioned in the provided information.

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