23andme is a private company offering genotyping. Consenting customers were asked the following questions: ‘Have you ever been diagnosed by a doctor with near-sightedness (near objects are clear, far objects are blurry)?’ and ‘Are you near-sighted (near objects are clear, far objects are blurry)?’; and with the same descriptor, ‘What vision problems do you have?’ and ‘Prior to your LASIK eye surgery, what vision problems did you have?’. These questions identified 106 086 probable myopia cases and 85 757 controls used in subsequent meta-analysis (N = 191 841).33
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