Residents of Wales diagnosed for the first time with at least one of 17 long-term conditions between January 2000 and December 2021 were identified using ICD-10 or Read v2 codes (Supplementary Tables S2 and S3). The conditions included were anxiety disorders, asthma, atrial fibrillation, coronary heart disease (CHD), chronic kidney disease (CKD), chronic obstructive pulmonary disease (COPD), dementia, depression, diabetes mellitus, epilepsy, heart failure, hypertension, inflammatory bowel disease (IBD), osteoporosis, peripheral vascular disease (PVD), rheumatoid arthritis, and stroke and transient ischaemic attack (TIA). These conditions comprise most of the general practice ‘Quality and Outcomes (QOF) Framework’.13 In addition, individuals diagnosed with three diabetes subtypes (type 1, type 2, undetermined) were identified using an algorithm.14 (link) ‘Undetermined type diabetes’ was assigned when criteria for type 1 or type 2 were not met.
The final study dataset excluded records missing week of birth or sex, or where the diagnosis date was before birth or after death dates.
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