Example 13
In a reaction bottle, p-nitroaniline (69 mg, 0.5 mmol), catalyst (28 mg, 0.05 mmol), di-tert-butyl peroxide (138 μL, 0.75 mmol), and ethylbenzene (7 mL) were added sequentially. The reaction was carried out at 140° C. for 16 hours. After the reaction was completed, it is cooled to room temperature. The product was purified by column chromatography eluting with ethyl acetate/petroleum ether with a volume ratio of 1:20, a yield of 80%.
The product was dissolved in CDCl3 (ca. 0.4 mL), sealed, and characterized on a Unity Inova-400 NMR apparatus at room temperature: 1H NMR (400 MHz, CDCl3, TMS): 7.98-7.97 (m, 2H), 7.37-7.30 (m, 4H), 7.27-7.23 (m, 1H), 6.47-6.43 (m, 2H), 4.95 (d, J=4.8 Hz, 1H), 4.58 (q, J=6.4 Hz, 1H), 1.57 (d, J=6.8 Hz, 3H) ppm.
