Colorectal Cancer Tissue Collection

We collected primary tumor tissues and paired normal colorectal tissues (> 5 cm distance from the cancer tissue margin) from 40 CRC patients from the Zhongnan Hospital of Wuhan University (Wuhan, China). All enrolled patients were definitively diagnosed with colorectal adenocarcinoma by histopathology, and none had received neoadjuvant radiotherapy or/and chemotherapy before undergoing resection. In addition, all the enrolled patients in the group had corresponding available survival data. This study was endorsed by the Ethics Committee of Zhongnan Hospital of Wuhan University in compliance with the Declaration of Helsinki. Informed consent was obtained from all the patients before sample collection.