In total, 36 participants were included in the study with maxillary or mandibular non-vital single rooted premolar teeth showing tenderness to percussion.
Exclusion criteria: pregnant women, patients who had received antibiotic treatment during the last 3 months, patients having more than one tooth requiring root canal treatment, teeth with periodontal probing depth >4mm, teeth that couldn't be isolated with a rubber dam, teeth with previous root canal treatment, or teeth with fluctuant facial swelling where emergency management should include incision and drainage.
Patients were randomly assigned into two groups (n=18/group) according to the intra-canal medication used, using a computer generated random number table at the Center of Evidence-based Dentistry (EBD), Cairo University. The assistant supervisor generated the random sequence and assigned the participants to the intervention or control groups.
Experimental group: double antibiotic paste (DAP); control group: calcium hydroxide paste (CH). All clinical procedures were performed by a single endodontist.
Exclusion criteria: pregnant women, patients who had received antibiotic treatment during the last 3 months, patients having more than one tooth requiring root canal treatment, teeth with periodontal probing depth >4mm, teeth that couldn't be isolated with a rubber dam, teeth with previous root canal treatment, or teeth with fluctuant facial swelling where emergency management should include incision and drainage.
Patients were randomly assigned into two groups (n=18/group) according to the intra-canal medication used, using a computer generated random number table at the Center of Evidence-based Dentistry (EBD), Cairo University. The assistant supervisor generated the random sequence and assigned the participants to the intervention or control groups.
Experimental group: double antibiotic paste (DAP); control group: calcium hydroxide paste (CH). All clinical procedures were performed by a single endodontist.
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