Antimalarial Compounds Acquisition Protocol

Chloroquine diphosphate, mefloquine, quinine, and pyrimethamine were obtained from Sigma-Aldrich (Saint-Quentin-Fallavier, France). Artemisinin was obtained from TCI Europe N.V. (Eschborn, Germany) and atovaquone from GlaxoSmithKline (Brentford, UK). Artesunate was obtained from Sanofi (Paris, France) and artemether from Rhone Poulenc Rorer (Paris, France). Dihydroartemisinin and monodesetylamodiaquine (amodiaquine/AQ) were obtained from WWARN (http://www.wwarn.org/). Artemisone was synthesized according to published protocols (19 (link)).

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Ménard S., Ben Haddou T., Ramadani A.P., Ariey F., Iriart X., Beghain J., Bouchier C., Witkowski B., Berry A., Mercereau-Puijalon O, & Benoit-Vical F. (2015). Induction of Multidrug Tolerance in Plasmodium falciparum by Extended Artemisinin Pressure. Emerging Infectious Diseases, 21(10), 1733-1741.

Publication 2015

Chloroquine diphosphate mefloquine quinine pyrimethamine atovaquone Artesunate

Amodiaquine Artemether Artemisinin Artemisone Artesunate Atovaquone Chloroquine diphosphate Dihydroartemisinin Mefloquine Pyrimethamine Quinine

Corresponding Organization :

Other organizations : Université Toulouse III - Paul Sabatier, Laboratoire de Chimie de Coordination, Institut Pasteur, Centre Hospitalier Universitaire de Toulouse

Top 5 similar protocols

Variable analysis

independent variables

Chloroquine diphosphate
Mefloquine
Quinine
Pyrimethamine
Artemisinin
Atovaquone
Artesunate
Artemether
Dihydroartemisinin
Monodesetylamodiaquine (amodiaquine/AQ)
Artemisone

dependent variables

Not explicitly mentioned

control variables

Not explicitly mentioned

controls

Positive control: Not specified
Negative control: Not specified

Annotations

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