Mouse Lines for Atoh1 Lineage Tracing

The following mouse lines were used in this study: Atoh1^lacZ/+ (catalog #005970, The Jackson Laboratory); Atoh1^Cre/+ (Yang et al., 2010 (link)); Atoh1^FlpO^/+ (catalog #036541, The Jackson Laboratory); Atoh1^flox/+(catalog #008681, The Jackson Laboratory); mRx-Cre (Klimova et al., 2013 (link)); Ai65 (catalog #021875, The Jackson Laboratory); and Ai14 (catalog #007914, The Jackson Laboratory). Ai65F mice were generated by crossing the Ai65 mice to Sox2-Cre mice (catalog #008454, The Jackson Laboratory). All mice were housed in a level 3, American Association for Laboratory Animal Science-certified facility on a 14 h light/dark cycle. Husbandry, housing, killing, and experimental guidelines were approved by the institutional animal care and use committee at Baylor College of Medicine.

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Wu S.R, & Zoghbi H.Y. (2023). The Atoh1-Cre Knock-In Allele Ectopically Labels a Subpopulation of Amacrine Cells and Bipolar Cells in Mouse Retina. eNeuro, 10(11), ENEURO.0307-23.2023.

Publication 2023

Atoh1Cre/+ Sox2-Cre mice

Institutional animal care and use committee Medicine Mice Sox2

Corresponding Organization :

Other organizations : Baylor College of Medicine, Texas Children's Hospital

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Variable analysis

independent variables

Atoh1^lacZ/+
Atoh1^Cre/+
Atoh1^FlpO/+
Atoh1^flox/+
MRx-Cre

dependent variables

Not explicitly mentioned

control variables

All mice were housed in a level 3, American Association for Laboratory Animal Science-certified facility on a 14 h light/dark cycle
Husbandry, housing, killing, and experimental guidelines were approved by the institutional animal care and use committee at Baylor College of Medicine

positive controls

Ai65 mice
Ai14 mice

negative controls

Ai65F mice generated by crossing Ai65 mice to Sox2-Cre mice

Annotations

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