Brain scans with a 1.5 Tesla system (Siemens; Erlangen, Germany) were performed every two years. Radiologists involved were blind to the individuals’ diagnosis, EDSS score, age and other demographic and MS-related information. In the present study, we report data from the MRI taken at the first diagnosis. Diagnosis of MS was obtained according to these MRIs. Further, MRIs were evaluated by trained and experienced neurologists responsible for the diagnosis of MS.
The locations of lesions were classified as follows: supratentorial; infratentorial; whole brain. Spinal cord lesions were classified as cervical and thoracic.
Last, the number of gadolinium-enhancing lesions were reported for the brain and the spinal cord.
MRI is part of the first assessment and the assessments every two years, or in case that symptoms worsen unexpectedly and dramatically. MRIs were performed according to MAGNISM consensus guidelines [25 (link)]. The following brain sequences were acquired: Axial; T2W, T2FLAIR, contrast-enhanced-T1W and PD. Sagittal; T2W, STIR, contrast-enhanced-T1W. Further, the following spine sequences were performed: sagittal T2w, STIR, contrast-enhanced T1w. Axial T2w and contrast enhanced T1W.
The locations of lesions were classified as follows: supratentorial; infratentorial; whole brain. Spinal cord lesions were classified as cervical and thoracic.
Last, the number of gadolinium-enhancing lesions were reported for the brain and the spinal cord.
MRI is part of the first assessment and the assessments every two years, or in case that symptoms worsen unexpectedly and dramatically. MRIs were performed according to MAGNISM consensus guidelines [25 (link)]. The following brain sequences were acquired: Axial; T2W, T2FLAIR, contrast-enhanced-T1W and PD. Sagittal; T2W, STIR, contrast-enhanced-T1W. Further, the following spine sequences were performed: sagittal T2w, STIR, contrast-enhanced T1w. Axial T2w and contrast enhanced T1W.
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