This study is limited to spirometric indices, analysis of data on lung volumes and transfer factor being deferred to a later stage. Prediction equations were derived for the FEV1, FVC and FEV1/FVC across the entire age range. For children aged 3–7 years (an age range chosen because the forced expiratory time usually exceeds 1 s in older children), the FEV075 and FEV075/FVC were also derived. Data on FEV0.75, FEV0.75/FVC and forced expired flow when 75% of the FVC has been exhaled (FEF75) were available only for Caucasians. Data (N=36,831) on FEF25–75% were available in 21 datasets. As very few data became available on FEV0.5, this index was not analysed.
Protocol detail
Spirometric Reference Equations for All Ages
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Corresponding Organization :
Other organizations : Erasmus University Rotterdam
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Variable analysis
independent variables
- Not explicitly mentioned
- FEV1 (Forced Expiratory Volume in 1 second)
- FVC (Forced Vital Capacity)
- FEV1/FVC
- FEV0.75 (Forced Expiratory Volume in 0.75 seconds)
- FEV0.75/FVC
- FEF75 (Forced Expired Flow when 75% of the FVC has been exhaled)
- FEF25-75% (Forced Expiratory Flow between 25% and 75% of the FVC)
- Ethnicity (Caucasians)
- Not specified
- Not specified
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