QSM reconstruction was performed by estimating the total field via a non-linear fit of the mGRE,41 (link) obtaining the local field by the Projection onto Dipole Fields (PDF) method,42 (link) and computing susceptibility with the Morphology Enabled Dipole Inversion with automatic uniform cerebrospinal fluid zero reference (MEDI+0) algorithm.43 (link)–46 (link) Cerebral blood flow (CBF) maps (mL/100g/min) were generated from the ASL data using FuncTool (GE Healthcare, Waukesha, WI, USA). All images were co-registered and interpolated to the resolution of the QSM maps using the FSL FLIRT algorithm.47 (link),48 (link)
Protocol detail
Quantitative Susceptibility Mapping and Cerebral Blood Flow
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Cerebral blood flow
Cerebrospinal fluid
Inversion
Maps
Projection method
Reconstruction
Susceptibility
Corresponding Organization : Cornell University
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Variable analysis
independent variables
- Non-linear fit of the mGRE data to estimate the total field
- Projection onto Dipole Fields (PDF) method to obtain the local field
- Morphology Enabled Dipole Inversion with automatic uniform cerebrospinal fluid zero reference (MEDI+0) algorithm to compute susceptibility
- Quantitative susceptibility mapping (QSM)
- Cerebral blood flow (CBF) maps (mL/100g/min)
- All images were co-registered and interpolated to the resolution of the QSM maps using the FSL FLIRT algorithm
- Not specified
- Not specified
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