The noncorrected and motion-corrected images were reconstructed by applying an iterative dedicated reconstruction algorithm with maximum-likelihood expectation maximization (Myovation, Xeleris 3.1, GE Healthcare). The use of dedicated software (Make SA and Fil3DBatch, Xeleris 3.1, GE healthcare) allowed to reconstruct both the noncorrected and motion-corrected images using the exact same alignment and masking, excluding possible reproducibility errors.16 (link)
Each image was automatically normalized to the maximum peak activity and the 17-segmental uptake values were presented as the percentage of the maximum myocardial regional uptake. Total perfusion deficit (TPD) was automatically calculated for all scans (Quantitative Perfusion SPECT (QPS) 2009, Sedar Senai). TPD is defined as the percentage of segments below the predefined uniform average deviation threshold, as explained in detail by Berman et al.20 (link) Scans were displayed in the traditional short, vertical long, and horizontal long axes and reviewed using a color scale.
Each image was automatically normalized to the maximum peak activity and the 17-segmental uptake values were presented as the percentage of the maximum myocardial regional uptake. Total perfusion deficit (TPD) was automatically calculated for all scans (Quantitative Perfusion SPECT (QPS) 2009, Sedar Senai). TPD is defined as the percentage of segments below the predefined uniform average deviation threshold, as explained in detail by Berman et al.20 (link) Scans were displayed in the traditional short, vertical long, and horizontal long axes and reviewed using a color scale.
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