Deglycosylation and Purification of Lantipeptide
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Corresponding Organization : Howard Hughes Medical Institute
Variable analysis
- Enzymes used: Endoproteinase Glu-C, UDP-xylose
- Not explicitly mentioned
- Chemicals and enzymes purchased from Sigma-Aldrich, Fisher Scientific, Worthington Biosciences, Complex Carbohydrate Research Center, Integrated DNA Technologies, New England BioLabs, QIAGEN, Bruker, Takara Biosciences, Biorad Inc., Bacillus Genetics Stock Center (BGSC)
- E. coli NEB Turbo used as host for cloning and plasmid propagation
- E. coli BL21(DE3) SHuffle used as host for expression of deglycosublancin
- Nickel resin used for gravity-based purification of His-tagged peptides or proteins
- Gradient gels used for checking protein expression
- Plasmids pHCMC04 and pJOE8999 for molecular cloning in B. subtilis Δspβ
- B. subtilis Δ6 and plasmids encoding fluorescent proteins in Bacillus
- Cyanine-5-amine used
- Positive control: Not explicitly mentioned
- Negative control: Not explicitly mentioned
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