Comparative Analysis of Immune-Deficient Mice

C57BL/6 (JAX stock no. 000664), STAT6-deficient (JAX stock no. 005977), Tbx21-deficient (JAX stock no. 004648), IL-12p40-deficient (JAX stock no. 002693), RORɣt mutant (JAX stock no. 031393) [62 (link)], IFN-γ R1-deficient (JAX stock no. 003288), CD45.1 (JAX stock no. 002014), IFN-γ-deficient (JAX stock no. 002287), MHC class II-deficient (JAX stock no. 003584), and CD4-Cre (JAX stock no. 017336) mice were purchased at 6–8 weeks old from The Jackson Laboratory (Bar Harbor, ME) and used for experiments at 7–12 weeks old. IFN-γ floxed mice were acquired from Dr. Harty from the University of Iowa. For many of these strains, breeding colonies were established to supply experiments. Mice were handled and used according to regulations of the Institutional Animal Care and Use Committee at University of California, Davis.