A cross-sectional study was carried out from April to September 2014. The sample population was based on older adults (≥60 years) who were beneficiaries of the Mexican Institute of Social Security (IMSS) in Mexico City. Data were derived from the database of the “Cohort of Obesity, Sarcopenia and Frailty of Older Mexican Adults” (COSFOMA). The research protocol was reviewed and approved by the National Committee of Scientific Investigation as well as by the Ethics Committee for Health Investigation (COMBIOETICA09CE101520130424) of the IMSS (Registry Number: 2012-785-067). Written informed consent was obtained from all participants of the COSFOMA study.
Sample size was calculated under the assumption that 14.1% of community-dwelling older adults in Mexico City would present frailty,8 (link) with an accuracy of the expected proportion of the phenomenon of ±2% and a confidence level of 95%. The minimum sample size was 1,164 older adults.