Monitoring Animal Health in Research

All live animals were monitored daily for clinical signs under anesthesia twice a day. Body temperature was measured by inserting a soft probe attached to an Omron electronic digital stick thermometer (MC-BOMR, Omron Co.) into the rectum 2 cm from the anal margin for one minute [18] (link). All clinical signs were monitored from day 2 p.i.. Venous blood of biological indicators such as blood cell count using the Veterinary Multi-species Hematology System (Hemavet 950FS, Drew Scientific Co.) and evaluation of the viral load were performed.

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Zhang Y., Yang E., Pu J., Liu L., Che Y., Wang J., Liao Y., Wang L., Ding D., Zhao T., Ma N., Song M., Wang X., Shen D., Tang D., Huang H., Zhang Z., Chen D., Feng M, & Li Q. (2014). The Gene Expression Profile of Peripheral Blood Mononuclear Cells from EV71-Infected Rhesus Infants and the Significance in Viral Pathogenesis. PLoS ONE, 9(1), e83766.

Publication 2014

Hemavet 950FS

Anal Anesthesia Animals Blood cell count Body temperature Rectum Thermometer Venous blood

Corresponding Organization :

Other organizations : Chinese Academy of Medical Sciences & Peking Union Medical College

Top 5 similar protocols

Variable analysis

independent variables

Anesthesia (twice a day)

dependent variables

Clinical signs
Body temperature
Blood cell count
Viral load

control variables

Soft probe attached to an Omron electronic digital stick thermometer (MC-BOMR, Omron Co.) used to measure body temperature
Veterinary Multi-species Hematology System (Hemavet 950FS, Drew Scientific Co.) used to evaluate blood cell count

controls

Positive control: Not specified
Negative control: Not specified

Annotations

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