5D EP-COSI MRI Acquisition Protocol

The 5D EP-COSI data was acquired on a Siemens 3 T Skyra scanner (Siemens Healthineer, Erlangen, Germany) with a dedicated “receive” 24-channel phase-array breast coil and a body “transmit” coil (FOV: 160 × 160 × 120mm³, 1.5 mL voxel volume, TR/TE were 1500/35 ms), running on VE11C software platform. 64 t₁ points sampled were used along F₁^{15 (link)} with a spectral bandwidth (SW) of 1250 Hz and 512 complex t₂ points, and a SW of 1190 Hz along F₂. A three-pulse sequence^{27 (link)} was employed before the global water suppression. A non-water suppressed scan with one t₁ point was acquired for eddy current phase correction and coil combination^{28 (link)}. Two spatial and one spectral dimensions (k_y,k_z,t₁) were non-uniformly sampled with an exponentially-weighted sampling density along t₁ and gaussian sampling density along the k_y-k_z plane for an acceleration factor of 8. The total scan time was 28 min and 48 s.

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Joy A, & Thomas M.A. (2023). Enhanced spectral resolution for correlated spectroscopic imaging using inner-product and covariance transform: a pilot analysis of metabolites and lipids in breast cancer in vivo. Scientific Reports, 13, 16809.

Publication 2023

Siemens 3 T Skyra scanner

Acceleration Body Breast Factor 8 Pulse Scan

Corresponding Organization :

Other organizations : University of California, Los Angeles

Top 5 similar protocols

Variable analysis

independent variables

Magnetic field strength (3 T)
Receive coil (24-channel phase-array breast coil)
Transmit coil (body coil)
Field of view (FOV: 160 × 160 × 120mm^3)
Voxel volume (1.5 mL)
Repetition time (TR: 1500 ms)
Echo time (TE: 35 ms)
Software platform (VE11C)
Number of t1 points sampled (64)
T1 spectral bandwidth (1250 Hz)
Number of t2 points sampled (512)
T2 spectral bandwidth (1190 Hz)
Three-pulse sequence before global water suppression
Non-uniform sampling (exponential along t1, Gaussian along ky-kz)

dependent variables

5D EP-COSI data

control variables

Non-water suppressed scan with one t1 point for eddy current phase correction and coil combination

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