Integrative Analysis of Bladder Cancer

We from the cancer genome atlas (TCGA) database (https://portal.gdc.cancer.gov/) to download the bladder cancer patients (including 414 samples of bladder cancer and 19 adjacent non tumor samples) expression of the spectral data, clinical information, somatic mutation. From Gene Expression Omnibus (GEO) database (https://cancergenome.nih.gov/) download GSE13507 (n = 165) and GSE32894 (n = 224) as an independent verification of the queue. The list of genes involved in glutamine metabolism was obtained from the GenesCards database.

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Xu Y., Xia Z., Sun X., Wei B., Fu Y., Shi D, & Zhu Y. (2023). Identification of a glutamine metabolism reprogramming signature for predicting prognosis, immunotherapy efficacy, and drug candidates in bladder cancer. Frontiers in Immunology, 14, 1111319.

Publication 2023

Cancer Cancer of bladder Genes Genome Glutamine Metabolism Mutation Patients Somatic Tumor

Corresponding Organization : China Medical University

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Variable analysis

independent variables

Bladder cancer samples
Adjacent non-tumor samples
GSE13507 dataset (n = 165)
GSE32894 dataset (n = 224)

dependent variables

Expression of spectral data
Clinical information
Somatic mutation

control variables

Genes involved in glutamine metabolism

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