Aortic Valve Geometric Modeling

The aortic valve geometric model was established by a previously described method with modification (Jernigan et al., 2007 (link); Nappi et al., 2020 (link)). Briefly, the ascending aorta CTA images in the DICOM format were imported into Mimics 10.01 software (Materialise, Leuven, Belgium). Then, based on the tissue density of cardiac valve, set the range of threshold between 329 to 560 Hounsfield units, and 3D reconstruction was performed using ‘Calculate 3D’ to obtain the geometric model of the aortic valve and ascending aortic arch. Next, the 3D solid model of aortic leaflets was built through meshes using the Remesh module in Magics.

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Li G., Shen N., Deng H., Wang Y., Kong G., Shi J., Dong N, & Deng C. (2023). Abnormal mechanical stress on bicuspid aortic valve induces valvular calcification and inhibits Notch1/NICD/Runx2 signal. PeerJ, 11, e14950.

Publication 2023

Aortic Aortic arch Aortic valve Ascending aorta Cardiac valve Reconstruction Tissue

Corresponding Organization :

Other organizations : Union Hospital, Huazhong University of Science and Technology, Zhejiang University

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Variable analysis

independent variables

Tissue density of cardiac valve
Range of threshold (329 to 560 Hounsfield units)

dependent variables

3D reconstruction of the geometric model of the aortic valve and ascending aortic arch

control variables

DICOM format of the ascending aorta CTA images
Mimics 10.01 software (Materialise, Leuven, Belgium)

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