Stability Evaluation of Optimum SPs

The optimum SPs formulation was stored for 90 days at 25°C and 4°C. Samples were taken from fresh SPs, after 45 days and after 90 days. The storage effect was evaluated by the comparison between the first and the after storage results in respect of EE%, VS, PDI and ZP.18 (link) Student’s t-test was used to analyze the results statistically using SPSS^® program 22.0 (USA). A significant difference was considered at P ≤ 0.05.

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Abdelbari M.A., El-mancy S.S., Elshafeey A.H, & Abdelbary A.A. (2021). Implementing Spanlastics for Improving the Ocular Delivery of Clotrimazole: In vitro Characterization, Ex vivo Permeability, Microbiological Assessment and In vivo Safety Study. International Journal of Nanomedicine, 16, 6249-6261.

Publication 2021

SPSS® program 22.0

Sps formulation Student

Corresponding Organization : Cairo University

Other organizations : October 6 University

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Variable analysis

independent variables

Storage temperature (25°C and 4°C)

dependent variables

Encapsulation efficiency (EE%)
Vesicle size (VS)
Polydispersity index (PDI)
Zeta potential (ZP)

control variables

Fresh SPs (samples taken at 0 days)
Samples taken at 45 days and 90 days

additional information

Student's t-test was used to analyze the results statistically using SPSS® program 22.0 (USA).
A significant difference was considered at P ≤ 0.05.

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