Web of Science, Embase, PubMed, Cochrane Library, China National Knowledge Infrastructure, Wanfang Data Knowledge Service Platform databases were subjected to study retrieving, from the earliest records to November 2022. International databases were searched using the key words (PNPLA3 gene or PNPLA3 polymorphism or patatin-like phospholipase domain-containing pro-tein3) and (nonalcoholic fatty liver disease or NAFLD or nonalcoholic steatohepatitis) and their possible combination. There was no limitation to language. Ethnicity and country restrictions were not applied.
Protocol detail
PNPLA3 Gene Variants and NAFLD
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Corresponding Organization : Krirk University
Other organizations : Tianjin University of Traditional Chinese Medicine, Saga University, Shandong University of Traditional Chinese Medicine
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Variable analysis
independent variables
- PNPLA3 gene
- PNPLA3 polymorphism
- Patatin-like phospholipase domain-containing protein3
- Nonalcoholic fatty liver disease
- NAFLD
- Nonalcoholic steatohepatitis
- Control variables not explicitly mentioned.
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