Extended criteria donors were defined according to the Eurotransplant Foundation rules by the following criteria: donor age >65 years, ICU stay with ventilation > 7 days, donor BMI > 30 kg/m2, hepatic steatosis > 40%, serum sodium > 165 mmol/L, alanine aminotransferase (ALT) > 105 U/L, aspartate aminotransferase (AST) > 90 U/L, total bilirubin > 3 mg/dL, and DCD [42 (link)].
Normothermic machine perfusion (NMP) was introduced at our center in February 2018 and has meanwhile been implemented in a daily routine for the following indications [43 (link)]:
Donor-related: in cases of ECD, especially if prolonged ischemia times are expected
Recipient-related: in cases of surgically highly complex recipients or high-risk patients
Logistic-related: in case of limited resources (e.g., parallel organ transplantations or overlap with other urgent interventions).