The aim of the experiment was to determine if standard laboratory rats (Long–Evans) will voluntarily consume ethanol when given intermittent-access to 20% ethanol using a 2-bottle-choice drinking paradigm without the use of sucrose fading. Twelve ethanol-naïve Long–Evans rats (360 ± 7 g) were given intermittent-access to 20% ethanol, as described above, for 20 drinking sessions (45 days). The ethanol and water intake was recorded on each ethanol day (no data collected during the 12th drinking session). In addition, the intake of water was recorded on the water days to enable comparison of the total fluid intake between the ethanol days (ethanol + water) and the water days.
Protocol detail
Voluntary Ethanol Consumption in Rats
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Corresponding Organization :
Other organizations : Ernest Gallo Clinic and Research Center, University of California, San Francisco, National Institute on Drug Abuse, National Institutes of Health, Medical University of South Carolina
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Variable analysis
independent variables
- Intermittent-access to 20% ethanol
- Ethanol intake
- Water intake
- Long-Evans rat strain
- Rat weight (360 ± 7 g)
- Number of drinking sessions (20)
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