Standardized Prostate Multiparametric MRI Evaluation

All patients underwent a multiparametric MRI as previously described.^{15 (link)} Briefly, MRIs were performed using a 3.0 T magnet (Achieva, Philips Healthcare) with an endorectal coil (BPX-30, Medrad^®) for all initial evaluation scans. For most subsequent followup scans after the initial evaluation scan, endorectal coil was not used. Prostate MRI studies underwent standardized radiological evaluation by 2 highly experienced genitourinary radiologists. All lesions subsequent to April 2015 were assigned an assessment category using the standardized PI-RADS^™ guidelines.^{16 (link)} Lesions identified before the adoption of the PI-RADS system were graded using the National Institutes of Health suspicion score system, previously demonstrated to correlate to the PI-RADS system.^{17 (link),18 (link)} In preparation for biopsy, lesions were identified, labeled and segmented by 1 radiologist using DynaCAD^® software.

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Yerram N.K., Long L., O’Connor L.P., Wang A.Z., Ahdoot M., Lebastchi A.H., Gurram S., Zeng J., Chalfin H., Harmon S.A., Mehralivand S., Merino M.J., Parnes H.L., Choyke P.L., Shih J., Wood B.J., Turkbey B, & Pinto P.A. (2020). Magnetic Resonance Imaging-Targeted and Systematic Biopsy for Detection of Grade Progression in Patients on Active Surveillance for Prostate Cancer. The Journal of urology, 205(5), 1352-1360.

Publication 2020

Achieva BPX-30

Biopsy Genitourinary Multiparametric mri Patients Prostate Radiological Radiologist Rads Scan

Corresponding Organization :

Other organizations : National Cancer Institute, National Institutes of Health, Frederick National Laboratory for Cancer Research

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Variable analysis

independent variables

Multiparametric MRI

dependent variables

Lesion assessment category (PI-RADS or NIH suspicion score)

control variables

Magnet strength (3.0 T)
Imaging equipment (Achieva, Philips Healthcare)
Endorectal coil (BPX-30, Medrad)
Radiological evaluation by 2 highly experienced genitourinary radiologists

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